blood-brain barrier (BBB) Device

Researchers fabricated an artificial device reproducing a 1:1 scale model of the blood-brain barrier (BBB), the anatomical and functional structure that protects the central nervous system from external substances, such as contaminants, but also drugs when they are injected intravenously into the body. The device will be fundamental for studying new therapeutic strategies to overcome blood-brain barrier and treat brain diseases.

Researchers at IIT-Istituto Italiano di Tecnologia fabricated an artificial device reproducing a 1:1 scale model of the blood-brain barrier (BBB), the anatomical and functional structure that protects the central nervous system from external substances, such as contaminants, but also drugs when they are injected intravenously into the body. The device, which is a combination of artificial and biological components, will be fundamental for studying new therapeutic strategies to overcome blood-brain barrier and treat brain diseases, such as tumours.

The device is described in a paper published today by the scientific journal Small and highlighted by the journal inside cover: it is a microfluidic device that combines artificial components made with 3-D advanced microfabrication techniques (two-photon lithography) and biological ones, that is endothelial cells (the cells covering blood vessels).

For more details visit:
https://materialscience.materialsconferences.com

Comments

Novel aspects of Nanotubes

A nanotube is a tubular particle made out of an extensive number of carbon atoms. Nanotubes having a wide range of application in various fields such as Photovoltaic cells , targeted drug delivery, automobile industries, aerospace so on. Now as per the recent studies, Researchers state that the weak van der Waals forces between the inner surface of the nanotube and the water molecules are strong enough to snap the oxygen and hydrogen atoms into place. In the case of a two-dimensional ice, the molecules freeze regardless of the temperature and research provides valuable insight on ways to leverage atomic interactions between nanotubes and water molecules to fabricate nanochannels and energy-storing nanocapacitors. Scientists built molecular models of carbon and boron nitride nanotubes with adjustable widths. They found boron nitride is best at obliging the state of water when the nanotubes are 10.5 angstroms wide. The scientists definitely realized that hydrogen particles in

Replacement of lithium-ions by sodium-ions for high capacity rechargeable batteries.

Lithium-ion batteries (LIB) are rechargeable and are generally utilized in workstations, cell phones and completely electric vehicles. The electric vehicle is a critical innovation for battling contamination in urban areas and understanding a time of clean maintainable transport. Anyway, lithium is costly and assets are unevenly dispersed over the planet. A lot of drinking water is utilized in lithium extraction and extraction strategies are ending up more vitality serious as lithium request rises an “own goal” regarding manageability. With the consistently expanding interest for electric cars, the requirement for rechargeable batteries is rising significantly, so there is a distinct fascination in finding a charge transporter other than lithium that is modest and effortlessly open. Sodium is cheap and can be found in seawater so is practically boundless. In any case, sodium is a bigger particle than lithium, so it isn't conceivable to just "swap" it for lithium i

New manufacturing technology: Processing glass like a polymer

Unadulterated quartz glass is very straightforward and impervious to warm, physical, and substance impacts. These are ideal essentials for use in optics , information innovation or therapeutic building. For proficient, superb machining, be that as it may, satisfactory procedures are inadequate. "It has dependably been a major test to consolidate profoundly unadulterated quartz glass and its phenomenal properties with a basic organizing innovation. " The researchers blend glass particles of 40 nanometers in estimate with a fluid polymer, shape the blend like a wipe cake, and solidify it to a strong by warming or light introduction. The subsequent strong comprises of glass particles in a network at a proportion of 60 to 40 vol%. The polymers demonstration like a holding operator that holds the glass particles at the correct areas and, thus, keeps up the shape. This "Glassomer" can be processed, turned, laser-machined or handled in CNC machines simply like a cu

31st Materials Science and Engineering Conference: Advancement & Innovations

Search This Blog